Tuesday, 11 August 2015

Paederia stink Summary (All / effects / data and information)

Paederia stink
Summary (All / effects / data and information is essential benefits)
It seems Paederia stinky herb used traditionally for a variety of purposes to revolve around either (especially anti-diarrhea, anti-dysentery) and also activated for the health of the intestine men's health.

There is very limited evidence for action, and bioactive is not currently known. The case seems to have anti-inflammatory and anti-oxidant that are common to most of the effects of herbs, with no evidence to suspect that any of these mechanisms is remarkable to behold.

According to one study, an increase in the dose and time depenendent in semen production and secretion of the hormone testosterone in male rats with exciting effects aphrodisiac erectogenic and effects; and supports this study the initial idea that this herb can increase male strength and vitality, but you need replication. The main biologically active research also to be wise.

Although no known toxicities associated with this herb at this moment in time, there was a large number of research toxicity.



What You Should Know
Also known as

Prasarini, Akkar Sekuntut, Gandhali
Paederia stinky (Rubiaceae family) is the Central and Eastern Himilayas plant grows up 5,000 meters or more, Prasarini is called in India, [1] Gandhali, [2] and Akkar Sekuntut in Malaysia. [3] you have any use recorded for rheumatoid arthritis and difficult job, besides being aphrodisiac, resulting in a glow, and improve semen standards.

It is considered very aromatic and sometimes eaten as cooking dish, whether raw or steamed. [3]


1.2. Installation

Paederine, Paederone, Paederolone and Paederenine [3]
Hentriacontane [1]
Hentriacontanol [1]
Glycosides Irioid [4]
Alcohol Cyril [1]
Methylemercaptan [1]
Palmitic acid (fatty acids in the diet) [1]
Ursolic acid [1]
Stigmasterol, campesterol, sitosterol and [1]
There were more than 77 volatile oils components. [5]

Phenolic content of fresh leaves can be up to 62.64 +/- 1.32, while premium stems can be up to 60.93 +/- 3.40 (equivalent mg ​​g / Alwerleik acid); and both are rejected after drying. [3]



2. nerves

21. Bah

In mature mice sexually because of 50-200mg / kg extract ethanol from Paederia stinky, Bah increase confirmed in pace (231%) and lower mount assembly latency (31.2%) along with increasing the frequency of intervention (222%) and decreased latency intervention (21% ); and all the effects were dose and time dependent, with peak values ​​(particular) is reached at 200 mg / kg after 28 days. [1] sexy aphrodisiac effects (the highest dose in 28 days) was similar to an active control of 0.5 mg / kg of testosterone (shots) every two weeks. [1]



3. interact with hormones

3.1. Testosterone

An increase in testosterone has been observed in the blood in healthy mice given 100-200mg / kg of ethanol extract (not 50 mg / kg) for 28 days, all of the highest dose included in the scope of the oscillation / ml 4- 4.5ng (derived from the value of Table) to the control of a little less than 2 ng / L; significant increases in testosterone hardly noticed in day 15 only in the highest dose group. [1]



4. Inflammation and Immunology

4.1. Mechanisms

Paederia stink seems to have some anti-inflammatory effects as evaluated by a test of granuloma formation in mice, where injection 100-200mg / kg exceeded stinky Paederua active control (100 mg / kg of vinyl). [6]



5. oxidation reactions

5.1. Mechanisms

Fresh leaves showed Paederia stink of in vitro antioxidant potential of quercetin with greater force, but less than that of vitamin E in test beta-carotene oxidation. [3] have been observed similar trends in free radical ABTS test, with leaves, but not more than exceeded quercetin Vitamin C as an active control. [3]



6. interactions bodies

6.1. Rod

I noticed a study in male rats using 50-200mg / kg of ethanol for 28 days an increase in penile erection index (PEI) with 100-200mg / kg at day 15 (175%, no dose dependency) and all 28 doses per day (154 -289%); both of which topped the active control of 0.5 mg / kg every two weeks testosterone. [1]


6.2. Testicles

28 days of supplementation was 50-200mg / kg of ethanol extract of Paederia stinky able to increase the weight of the testes (5.9%), epididymis (9.3%) and seminal vesicles (7.9%) without relying on what seems dose. It has been observed [1] In the histological study, the effect of slightly increased vascular and sperm concentrations in the testicular Sertoli cells were expanded and highly processed. [1]


63. Prostate

Study mice using 50-200mg / kg of ethanol extract of Paederia stink for 28 days Note that although there is a trend to increase the weight of the prostate that this increase were not statistically significant. Active control of 0.5 mg / kg every two weeks Testosterone also did not reach statistical significance. [1]


6.4. Bowels

In test diarrhea caused by castor oil, can 100-500mg / kg of ethanol extract of Paederia stinky have the perverse effect of acute diarrhea with 500 mg / kg only be relevant to 6 hours. [7] it has been observed adverse effects of diarrhea also in the test of magnesium sulfate, and tend to reduce intestinal motility caused by cisplatin and barium sulfate. [7]

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